Most of Zetias side effects should go away within a few days or weeks. Despite having lower total cholesterol than white people, African Americans are at greater risk of dying from heart disease. . Statins are drugs used to lower cholesterol. However, if the side effects last longer than . To help you decide whether Zetia is a good treatment choice for you, talk with your doctor. Do my other medications increase my risk of side effects with Zetia? POTS-related fatigue is physical in nature . Forget HDL and LDL. tightness of chest or wheezing. But, they can have side effects and might not be right for you. Postural orthostatic tachycardia syndrome (POTS) is one of a group of disorders that have orthostatic intolerance (OI) as their primary symptom. The generic form of Zetia costs about the same as the generic form of Lipitor. Zetia may not be right for you if you have certain medical conditions or other factors that affect your health. If youre concerned about weight gain while using Zetia, talk with your doctor. What is considered high cholesterol? Chylomicrons help your body, low-density lipoproteins (LDL), sometimes referred to as bad cholesterol, high-density lipoproteins (HDL), sometimes referred to as good cholesterol, triglycerides, which are a type of fat that are building blocks of cholesterol, Apo B (high levels of this protein are a sign of high cholesterol), non-HDL cholesterol (calculated by subtracting your HDL cholesterol level from your total cholesterol), were reduced by an average of 13% to 14% in people who used Zetia, ranged from not changing to being reduced by an average of 1% in people who used a placebo, were reduced by an average of 18% in people who used Zetia, increased by an average of 1% in people who used a placebo, decreased by an average of 13% to 14% in people who used Zetia alone, decreased by an average of 15% to 40% in people who used a statin alone, depending on the statin used, decreased by an average of 24% to 46% in people who used Zetia and a statin, depending on the statin used, ranged from decreasing by an average to 1% to increasing by an average of 4% in people who took a placebo, decreased by an average of 19% to 20% in people who used Zetia alone, decreased by an average of 20% to 54% in people who used a statin alone, depending on the statin used, decreased by an average of 34% to 61% in people who used Zetia and a statin, depending on the statin used. It is not yet clear what are the causes of POTS disease. The underlying cause is not known, although it sometimes follows bedrest after injury or illness. You may find your symptoms are worse in the morning, and they may change from day to day. If you have any questions about eating certain foods while taking Zetia, talk with your doctor. diarrhea. For more information on the possible side effects of Zetia, talk with your doctor or pharmacist. Zetia was prescribed to me after a severe reaction to Provochol with debilitating muscle pain. Zetia and Lipitor are both brand-name drugs. Postural orthostatic tachycardia syndrome (POTS) is a form of dysautonomia, or a malfunction of the autonomic nervous system. Lipitor ( atorvastatin) and Zetia ( ezetimibe) are used to lower cholesterol levels in the blood. It can develop suddenly or gradually over time. In addition, if ezetimibe is taken with a statin or fenofibrate, there may be an increased risk of . For this purpose, Zetia may be used alone or with fenofibrate. zetia. Get medical help right away, if you have any of the symptoms listed above. Zetia can also be used with statin drugs in adults. Examples of statin drugs include atorvastatin (Lipitor) and simvastatin (Zocor). joint pain *. 4. The current stance of the Food and Drug Administration (FDA) is to avoid using expired medications. Note: Some of the drugs listed here are used off-label to treat these specific conditions. They may be able to help determine whats causing your hair loss. Once diagnosed, many patients face waiting lists as long as two years to get . It may take about 2 weeks for your cholesterol levels to improve after you start taking Zetia. However, be sure to take the dosage your doctor prescribes for you. Since every POTS patient is different, some may primarily experience gastrointestinal symptoms, such as nausea, vomiting or poor feeding, Berger explained. Bethenny Frankel is opening up about her health issue, explaining to her Instagram followers about her battle with postural orthostatic tachycardia syndrome (POTS) after receiving comments about . Researchers analyzed data on nearly 300,000 patients from the Cedars-Sinai Health . voice changes. But new medications can help lower cholesterol and improve heart health. A decrease in the transport of intestinal cholesterol to the liver reduces stores of hepatic cholesterol. This includes grapefruit and grapefruit juice. Serious side effects from Zetia arent common, but they can occur. It belongs to a class of drugs called cholesterol absorption inhibitors. However, you may still experience muscle problems if you use Zetia alone. See the Mild side effects and Serious side effects sections above for more information. And talk with your doctor if you have any questions about eating certain foods with Zetia. Clinical studies for ezetimibe did not note any difference in weight in those that took the drug versus those that did not. Sharing this information can help you avoid potential interactions. In addition to Goff's specific symptoms, POTS can be associated with neurocognitive impairments or "brain fog"; problems with body temperature regulation; gastroenterological symptoms like nausea, abdominal pain, diarrhea, or constipation; and dark red-blue discoloration of the legs. For more information about how the drug is used, see the Zetia uses section below. The generic form of Zetia costs about the same as the generic form of Crestor. Read on to find out more about healthy cholesterol levels, and if a cholesterol level of 250 ml/dL is considered, Heart disease is a top cause of death in the U.S. There arent any foods that have been specifically reported to interact with Zetia. Statins are another type of medication used to lower cholesterol. If you have symptoms of a severe allergic reaction, such as swelling or trouble breathing, call 911 or your local emergency number right away. Zetia is sometimes used with medications in the statin drug class. Both drugs are typically taken once each day. * Sex and gender exist on spectrums. 1. Study on Ezetimibe Yielded Disappointing Results: Another reader wrote us shortly after learning of the results of a study that raised questions about ezetimibe: Q. The symptoms develop immediately and include dizziness and an intense headache. In studies, muscle problems commonly occurred in adults and children who took Zetia with statin drugs. Some people with POTS also may have one or more . It is created by eHealthMe based on reports of 45,364 people who have side effects when taking Zetia from the FDA, and is updated regularly. It isnt known how long adults and children experienced diarrhea while taking Zetia in these clinical studies. There are no known interactions between Zetia and alcohol. The autonomic nervous system is in charge of all bodily functions that we don't have to think about, such as: The sympathetic nervous system is part of the autonomic nervous system. Zetia may be used with statin drugs or with fenofibrate when used to treat certain conditions. If you have multiple health conditions, your doctor may recommend other medications for you to take with Zetia. Zetia may also increase the amount of cholesterol thats stored in your gallbladder. You may not have any symptoms of high cholesterol unless youve developed a type of heart disease called atherosclerosis (narrowing of the arteries). Some people experience mild side effects with Zetia. Your side effect notes can include things such as: Keeping notes and sharing them with your doctor will help your doctor learn more about how Zetia affects you. shaking and sweating. Different interactions can cause different effects. Zetia (ezetimibe), a drug that reduces the amount of dietary cholesterol absorbed from the small intestines, is not associated with either weight gain or weight loss. Postural orthostatic tachycardia syndrome (POTS) is a blood circulation disorder characterized by two factors: A specific group of symptoms that frequently occur when standing upright. The side effects from Zetia .. muscle weakness, joint pain, upper respiratory infectikns resemble the symptoms of malabsorption of Vitamin A,D, E and K. Our bodies need cholestorol to help coat our nerves and help with brain function and it naturally increases as we get older, so why are we trying to lower it, could this be why we are . Zetia isnt a statin drug. Do not use more Zetia than your doctor recommends. Crestor contains the active drug rosuvastatin. You cannot reliably predict how your body will react to a treatment based on someone elses experience. Zetia is approved to treat certain forms of high cholesterol in children ages 10 years and older when used with a low-cholesterol diet. Below are examples of these side effects. Fenofibrate belongs to the fibrate drug class. Grapefruit can prevent the breakdown of these drugs in your body. What causes POTS? POTS is a form of "autonomic dysregulation" (a nervous system disorder) in which your heart rate spikes upon standing (among other symptoms). But its not clear whether this side effect occurred in studies. Porphyrias are rare, mainly genetic disorders that affect the body's ability to make hemoglobin. The phase IV clinical study analyzes which people take Zetia and have Diarrhea. Zetia (ezetimibe) is a prescription drug used to treat certain types of high cholesterol in adults and children. Dont take an extra dose to make up for your missed dose. Zetias side effects are usually mild, especially if youre taking Zetia alone. Healthline Media does not provide medical advice, diagnosis, or treatment. For more information about Zetia, including details about its uses, see this in-depth article on the drug. Eating large meals can worsen hypotension in some individuals with dysautonomia (Mathias, 2000). Its not known if Zetia is safe to take during pregnancy. Using Zetia with medications in the fibrate drug class raises your risk of gallstones even more. Allergic reaction. weakness and fatigue (tiredness) headaches. Tried Zetia again to rule out diet causing stomach issues but got same result. They can give you tips on how to deal with any side effects that may be bothersome. Tell them about all prescription, over-the-counter, and other drugs you take. Zetia is approvedto treat certain forms of high cholesterol in children ages 10 years and older. POTS is commonly associated with low levels of fluid. If youre taking a statin drug with Zetia, they may recommend that you take a supplement called coenzyme Q10 (CoQ10). Ezetimibe is used along with a low cholesterol/low fat diet and exercise to help lower cholesterol in the blood. The generic is considered to be as safe and effective as the original drug. These symptoms can be signs of an infection. Zetia is FDA-approved to lower your total cholesterol level, and triglycerides are one part of your total cholesterol level. Medications in the fibrate drug class may increase the amount of cholesterol thats stored in your gallbladder. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. In addition, you may need to watch out for grapefruit. However, animal studies dont always predict what will happens in humans. Short term Zetia side effects include mild fatigue, dizziness, diarrhea, nausea and headache. Cholesterol can also be found in foods such as eggs, cheese, and meat. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Other interactions can increase side effects or make them more severe. Avoid storing this medication in areas where it could get damp or wet, such as bathrooms. Zetia is meant to be used as a long-term treatment. Zetia (ezetimibe) is prescribed to lower high cholesterol in adults and some children, along with a low cholesterol diet. Most patients will need at least 64 to 80 ounces (8 to 10 cups) of hydrating liquids throughout the day, such as water, broth, juice, or decaffeinated tea. You may wonder how often certain side effects occur with this drug, or whether certain side effects pertain to it. However, if youre taking Zetia with a statin drug, youll need to avoid eating grapefruit or drinking grapefruit juice. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. yellowing of your skin or the whites of your eyes, ahajournals.org/doi/10.1161/JAHA.118.009835, organon.com/product/usa/pi_circulars/z/zetia/zetia_pi.pdf, Alternatives to Statins for Lowering Cholesterol. Zetia (ezetimibe) is prescribed to lower high cholesterol in adults and some children, along with a low cholesterol diet. The following information is provided for clinicians and other healthcare professionals. It's Aimee Esther here! Ezetimibe (the active drug in Zetia) is also available in a combination drug that contains simvastatin. . Both drugs are typically taken once each day. However, excessive alcohol use can damage your liver over time. Both Zetia and Crestor come as tablets that are swallowed. Or they may recommend a product you apply to your skin, such as hydrocortisone cream. 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